TAS0728 Size:10 mg solid EW-7197 Hydrochloride also inhibits the

EW-7197 Hydrochloride also inhibits the epithelial-to-mesenchymal transition (EMT) in both TGFβ-treated breast cancer cells and 4T1 orthotopic-grafted mice

a potent and selective inhibitor of polo-like kinase 1

14: 1363-1369

CAS Number: 327036-89-5

is a novel PDK1 (phosphoinositide-dependent protein kinase 1) activator (Kd = 10

TAS0728 Size:10 mg solid EW-7197 Hydrochloride also inhibits theTAS0728 (TPC 107) is a potent, selective, orally active, irreversible and covalent binding inhibitor of HER2 (human epidermal growth factor receptor 2) with IC50 of 13 nM. TAS0728 inihibits BMX, HER4, BLK, EGFR, JAK3, SLK, LOK and human HER2 with IC50 of 4. 9 nM, 8. 5 nM, 31 nM, 65 nM, 33 nM, 25 nM, 86 nM and 36 nM, respectively. TAS0728 shows antitumor activity. Product information CAS Number: 2088323 16 2 Molecular Weight: 504. 58 Formula: