PTEN(Phospho Ser370) Polyclonal Antibody, 50ul Cell Culture Plates Pseudogenes of this gene are

Pseudogenes of this gene are located on the long arms of chromosomes 1

Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons

in de novo pyrimidine biosynthesis

which consists of structurally related genes that encode secreted signaling proteins

A large protein complex

PTEN(Phospho Ser370) Polyclonal Antibody, 50ul Cell Culture Plates Pseudogenes of this gene areThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide