PSB10 Rabbit Polyclonal Antibody, 50ul DNA Fragments It is a type I

It is a type I membrane protein

A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene| encoding a DNA binding protein| located on chromosome 11 is associated with leukemia

Mutations in this gene are associated with sensory/motor neuropathy with ataxia

The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily

A cis-acting segment found in the 5' UTR is involved in stress-dependent induction| resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions

PSB10 Rabbit Polyclonal Antibody, 50ul DNA Fragments It is a type IThe proteasome is a multicatalytic proteinase complex with a highly ordered ring shaped 20S core structure. The core structure is composed of 4 rings of 28 non identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP ubiquitin dependent process in a non lysosomal pathway. An essential function