BMP-4 Rabbit Polyclonal Antibody, 20ul Antibody Humanization APM2 gene is exclusively expressed

APM2 gene is exclusively expressed in adipose tissue

This gene encodes three main isoforms that differ in activities and subcellular location

Mutations in this gene are a cause of X-linked deafness-4| and the encoded protein may play a role in the maintenance of inner ear cells subjected to mechanical stress

When expressed in cells| this protein activated NF-kappaB and induced the phosphorylation of BCL10

It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1

BMP-4 Rabbit Polyclonal Antibody, 20ul Antibody Humanization APM2 gene is exclusively expresseddisease: Defects in BMP4 are the cause of microphthalmia syndromic type 6 (MCOPS6)