ETAR Polyclonal Antibody, 50ul[BT-AP03094] Cell Culture Studies of the mouse and

Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage

GO annotations related to this gene include phosphatase activity and protein tyrosine/serine/threonine phosphatase activity

homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions

Telomerase expression plays a role in cellular senescence| as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres

and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma

ETAR Polyclonal Antibody, 50ul[BT-AP03094] Cell Culture Studies of the mouse andEDNRA encodes the receptor for endothelin 1, a peptide that plays a role in potent and long lasting vasoconstriction. This receptor associates with guanine nucleotide binding (G) proteins, and this coupling activates a phosphatidylinositol calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants.