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Oct1 Monoclonal Antibody(7G1), 20ul Cell Culture & Maintenance Downstream targets of this nuclear

SKU: 98575135724

4.8
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Oct1 Monoclonal Antibody(7G1), 20ul Cell Culture & Maintenance Downstream targets of this nuclearThe OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160 amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.[supplied by OMIM, Jul 2010],

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Description

Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways

Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH

Two alternatively spliced transcript variants encoding the same isoform have been found for this gene

The CBC promotes pre-mRNA splicing

similar to other family members

Oct1 Monoclonal Antibody(7G1), 20ul Cell Culture & Maintenance Downstream targets of this nuclearThe OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160 amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.[supplied by OMIM, Jul 2010],

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