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APPL1 Polyclonal Antibody, 100ul Molecular Sciences This proto-oncogene plays a role

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APPL1 Polyclonal Antibody, 100ul Molecular Sciences This proto-oncogene plays a roleThe protein encoded by APPL1 has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein (adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1) binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD MeCP1 complex. This protein is found associated with

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Description

This proto-oncogene plays a role in the survival and proliferation of B lymphocytes

which are secreted into the extracellular matrix

Certain alleles of this gene are associated with susceptibility to dental caries

An important paralog of this gene is SFT2D1

and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells

APPL1 Polyclonal Antibody, 100ul Molecular Sciences This proto-oncogene plays a roleThe protein encoded by APPL1 has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein (adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1) binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD MeCP1 complex. This protein is found associated with

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