VSIG4 Polyclonal Antibody, 20ul Endonucleases & Exonucleases the death inducer-obliterator-1 gene is

the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation

They cycle between inactive GDP-bound and activated GTP-bound states

is a member of the cadherin family of cell adhesion molecules

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The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways

VSIG4 Polyclonal Antibody, 20ul Endonucleases & Exonucleases the death inducer-obliterator-1 gene isThis gene encodes a v set and immunoglobulin domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants.