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MerTK Polyclonal Antibody, 50ul Mechanical Pipette Interleukin-3 receptor subunit alpha encoded

SKU: 98308607327

4.5
SEK185.00 SEK235.00

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MerTK Polyclonal Antibody, 50ul Mechanical Pipette Interleukin-3 receptor subunit alpha encodedMERTK is a member of the MER AXL TYRO3 receptor kinase family and encodes a transmembrane protein, tyrosine protein kinase mer, with two fibronectin type III domains, two Ig like C2 type (immunoglobulin like) domains, and one tyrosine kinase domain. Mutations in MERTK have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

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Description

Interleukin-3 receptor subunit alpha encoded by IL3RA is an interleukin 3 specific subunit of a heterodimeric cytokine receptor

at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor

is widely expressed whereas the RBMY gene evolved a male-specific function in spermatogenesis

Alternatively spliced transcript variants encoding d

Mutations in this gene lead to spinal muscle atrophy with respiratory distress type 1

MerTK Polyclonal Antibody, 50ul Mechanical Pipette Interleukin-3 receptor subunit alpha encodedMERTK is a member of the MER AXL TYRO3 receptor kinase family and encodes a transmembrane protein, tyrosine protein kinase mer, with two fibronectin type III domains, two Ig like C2 type (immunoglobulin like) domains, and one tyrosine kinase domain. Mutations in MERTK have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

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