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SNF8 Rabbit Polyclonal Antibody, 20ul Cell Culture Dishes The encoded protein can act

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SNF8 Rabbit Polyclonal Antibody, 20ul Cell Culture Dishes The encoded protein can actThe protein encoded by this gene is a component of the endosomal sorting complex required for transport II (ESCRT II) which regulates the movement of ubiquitinylated transmembrane proteins to the lysosome for degradation. This complex also interacts with the RNA polymerase II elongation factor (ELL) to overcome the repressive effects of ELL on RNA polymerase II activity. Several transcript variants encoding different isoforms have been found for this

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Description

The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes

SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex

Angiogenesis inhibitor

It is a potential target for ubiquitination by the Nedd4 family of proteins

a childhood brain tumor

SNF8 Rabbit Polyclonal Antibody, 20ul Cell Culture Dishes The encoded protein can actThe protein encoded by this gene is a component of the endosomal sorting complex required for transport II (ESCRT II) which regulates the movement of ubiquitinylated transmembrane proteins to the lysosome for degradation. This complex also interacts with the RNA polymerase II elongation factor (ELL) to overcome the repressive effects of ELL on RNA polymerase II activity. Several transcript variants encoding different isoforms have been found for this

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