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SENP6 Polyclonal Antibody, 50ul Metabolic enzymes tool compounds RAN is a small GTP-binding

SKU: 98158284374

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SENP6 Polyclonal Antibody, 50ul Metabolic enzymes tool compounds RAN is a small GTP-bindingUbiquitin like molecules (UBLs), such as SUMO1 (UBL1; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex, as well as in stabilization of I kappa B alpha (NFKBIA; MIM 164008)

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Description

RAN is a small GTP-binding protein of the RAS superfamily that is associated with the nuclear membrane and is thought to control a variety of cellular functions through its interactions with other proteins

The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle

High levels of FAC1 were detected in fetal brain and in patients with neurodegenerative diseases

This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication

interleukin 3 regulated encoded by NFIL3 is a transcriptional regulator that binds as a homodimer to activating transcription factor (ATF) sites in many cellular and viral promoters

SENP6 Polyclonal Antibody, 50ul Metabolic enzymes tool compounds RAN is a small GTP-bindingUbiquitin like molecules (UBLs), such as SUMO1 (UBL1; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex, as well as in stabilization of I kappa B alpha (NFKBIA; MIM 164008)

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