Phospho-ATR (S428) Polyclonal Antibody, 100ul Vessels to a higher extent

to a higher extent

Mutations in this gene have been associated with Oguchi disease

The phosphorylation of RAD17 checkpoint clamp loader component is required for the DNA-damage-induced cell cycle G2 arrest

This protein can be activated by various ligands including interferon-alpha

The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation

Phospho-ATR (S428) Polyclonal Antibody, 100ul Vessels to a higher extentThe protein encoded by ATR (ATR serine threonine kinase) belongs the PI3 PI4 kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1,