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GRPR Polyclonal Antibody, 100ul Mechanical Pipette The protease domain of this

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GRPR Polyclonal Antibody, 100ul Mechanical Pipette The protease domain of thisGastrin releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin releasing peptide receptor. This receptor is a glycosylated, 7 transmembrane G protein coupled receptor that activates the

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Description

The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage

Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters

Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC

A pseudogene corresponding to this gene is found on chromosome 21q

It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes

GRPR Polyclonal Antibody, 100ul Mechanical Pipette The protease domain of thisGastrin releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin releasing peptide receptor. This receptor is a glycosylated, 7 transmembrane G protein coupled receptor that activates the

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