GHR Polyclonal Antibody, 50ul Apoptosis & Autophagy This transmembrane protein localizes to

This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins

A pseudogene corresponding to this gene is found on chromosome 5q

It probably plays a role in the regulation of acute-phase reaction| inflammation and hemopoiesis

MBTPS1 (membrane bound transcription factor peptidase

Mutations in this gene are associated with Leigh syndrome due to mitochondrial complex 1 deficiency

GHR Polyclonal Antibody, 50ul Apoptosis & Autophagy This transmembrane protein localizes toGHR encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature.