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HIF-1 beta Polyclonal Antibody, 20ul[BT-AP09890] Cell Culture & Maintenance This gene encodes a member

SKU: 97199370266

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HIF-1 beta Polyclonal Antibody, 20ul[BT-AP09890] Cell Culture & Maintenance This gene encodes a memberThis gene encodes a protein containing a basic helix loop helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co factor for transcriptional regulation by hypoxia inducible factor 1. Chromosomal translocation

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Description

This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) protein family| with an N-terminal PDZ domain| a central src homology 3 region (SH3)| and a C-terminal guanylate kinase-like (GUK) domain

It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2)

it is expressed at high levels in peripheral blood leukocytes

Transcripts may include the shared exon spliced to the gene-specific exons| or they may include only the gene-specific exons

These sterile and DNase/RNase-Free tips come in a convenient plastic rack packing

HIF-1 beta Polyclonal Antibody, 20ul[BT-AP09890] Cell Culture & Maintenance This gene encodes a memberThis gene encodes a protein containing a basic helix loop helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co factor for transcriptional regulation by hypoxia inducible factor 1. Chromosomal translocation

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