Vav(Phospho Tyr160) Polyclonal Antibody, 20ul Site-directed Mutagenesis lung and kidney

lung and kidney

Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease

The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity

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Alternatively spliced transcript variant encoding distinct isoforms have been observed

Vav(Phospho Tyr160) Polyclonal Antibody, 20ul Site-directed Mutagenesis lung and kidneyThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.