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SRp40 Polyclonal Antibody, 100ul Cell Dissociation enzyme regulation:Activated by phosphorylation on

SKU: 97127267345

4.1
PLN141.00 PLN178.00

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SRp40 Polyclonal Antibody, 100ul Cell Dissociation enzyme regulation:Activated by phosphorylation onThe protein encoded by SRSF5 (serine and arginine rich splicing factor 5) is a member of the serine arginine (SR) rich family of pre mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition

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Description

enzyme regulation:Activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39

Catalytic activity:Selective cleavage of Arg-|-Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor

May be involved in transferrin trafficking

The encoded protein is involved in several cellular processes| including autophagic vesicle formation| mitochondrial quality control after oxidative damage| negative regulation of the innate antiviral immune response| lymphocyte development and proliferation| MHC II antigen presentation| adipocyte differentiation| and apoptosis

An important paralog of this gene is SLC7A3

SRp40 Polyclonal Antibody, 100ul Cell Dissociation enzyme regulation:Activated by phosphorylation onThe protein encoded by SRSF5 (serine and arginine rich splicing factor 5) is a member of the serine arginine (SR) rich family of pre mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition

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