NUP62 Polyclonal Antibody, 100ul Drug Development and Evaluation 023 amino acid protein that

023 amino acid protein that contains one helical Rho-GAP domain and is encoded by a gene located on human chromosome 15

Mutations in this gene have been associated with autosomal recessive non-syndromic deafness and Usher Syndrome

The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma

widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells

but accumulates progressively throughout the S phase

NUP62 Polyclonal Antibody, 100ul Drug Development and Evaluation 023 amino acid protein thatThe nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG repeat containing nucleoporins and is localized to the nuclear pore central plug. This protein associates with the importin