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IOD2 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) This gene is mutated in

SKU: 96335828633

4.6
SEK185.00 SEK217.00

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IOD2 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) This gene is mutated inThe protein encoded by this gene belongs to the iodothyronine deiodinase family. It catalyzes the conversion of prohormone thyroxine (3,5,3',5' tetraiodothyronine, T4) to the bioactive thyroid hormone (3,5,3' triiodothyronine, T3) by outer ring 5' deiodination. This gene is widely expressed, including in thyroid, placenta, pituitary and brain. It is thought to be responsible for the 'local' production of T3, and thus important in influencing thyroid

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Description

This gene is mutated in congenital disorder of glycosylation type Ik

and are involved in intracellular trafficking

The enzyme catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans

and RNA splicing

Activity of this protein may be associated with obesity and other metabolic diseases

IOD2 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) This gene is mutated inThe protein encoded by this gene belongs to the iodothyronine deiodinase family. It catalyzes the conversion of prohormone thyroxine (3,5,3',5' tetraiodothyronine, T4) to the bioactive thyroid hormone (3,5,3' triiodothyronine, T3) by outer ring 5' deiodination. This gene is widely expressed, including in thyroid, placenta, pituitary and brain. It is thought to be responsible for the 'local' production of T3, and thus important in influencing thyroid

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