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TLE3 Rabbit Polyclonal Antibody, 100ul Insect Expression The deletion of one copy

SKU: 96287086192

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TLE3 Rabbit Polyclonal Antibody, 100ul Insect Expression The deletion of one copyThis gene encodes a transcriptional co repressor protein that belongs to the transducin like enhancer family of proteins. The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development. Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma. Alternate splicing results in multiple transcript variants. Additional

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Description

The deletion of one copy of this gene may be responsible for mental defects in patients with 3p- syndrome

The encoded protein acts as a homodimer and is involved in cell motility and cell-matrix interactions

This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) family of ATPases

The encoded protein is a centrosome-shuttling protein and plays an important role in cytokinesis

The deduced amino acid sequence exhibits 33% similarity with CD38

TLE3 Rabbit Polyclonal Antibody, 100ul Insect Expression The deletion of one copyThis gene encodes a transcriptional co repressor protein that belongs to the transducin like enhancer family of proteins. The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development. Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma. Alternate splicing results in multiple transcript variants. Additional

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