Casein Kinase I Alpha Monoclonal Antibody, 50ul Pipette Filler Mutations in this gene have

Mutations in this gene have been associated with Specific Granule Deficiency

Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma

The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events

and is resistant to harsh chemicals

Alternate transcription initiation sites result in two transcript variants of this gene

Casein Kinase I Alpha Monoclonal Antibody, 50ul Pipette Filler Mutations in this gene havecatalytic activity: ATP + a protein = ADP + a phosphoprotein.,function: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 on 'Ser 45'.,similarity: Belongs to the protein kinase superfamily.,similarity: Belongs to the protein kinase superfamily. CK1 Ser Thr protein kinase