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FA11 Rabbit Polyclonal Antibody, 20ul[BT-AP09941] Subcellular Fractions May be involved in pre-mRNA

SKU: 96149708226

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PLN111.00 PLN155.00

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FA11 Rabbit Polyclonal Antibody, 20ul[BT-AP09941] Subcellular Fractions May be involved in pre-mRNAThis gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains resulting in activated factor XIa a serine protease

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Description

May be involved in pre-mRNA splicing

Mutations in this gene result in alpha-2-plasmin inhibitor deficiency| which is characterized by severe hemorrhagic diathesis

Associates with the 9-1-1 complex

which may occur via its interaction with AIF

The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by SST

FA11 Rabbit Polyclonal Antibody, 20ul[BT-AP09941] Subcellular Fractions May be involved in pre-mRNAThis gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains resulting in activated factor XIa a serine protease

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