NSE2 Polyclonal Antibody, 20ul[BT-AP12036] NGS Oligos It plays a putative role

It plays a putative role in tumorigenic reversion and may control cell proliferation

This protein is a coiled-coil membrane protein that has been postulated to play a role in vesicle tethering and docking

Mutations in TBX3 cause ulnar-mammary syndrome

An important paralog of this gene is RNF167

This gene shares its 5' exon with the overlapping gene

NSE2 Polyclonal Antibody, 20ul[BT-AP12036] NGS Oligos It plays a putative roleE3 SUMO protein ligase component of the SMC5 SMC6 complex, a complex involved in DNA double strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1 SMC3 cohesin complex to double strand breaks. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein ligase activity is required for