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Rpb1 CTD(Phospho-Thr4) Rabbit Polyclonal Antibody, 50ul[BT-AP12338] Immunology Mutations in this gene are

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Rpb1 CTD(Phospho-Thr4) Rabbit Polyclonal Antibody, 50ul[BT-AP12338] Immunology Mutations in this gene areThis gene encodes the largest subunit of RNA polymerase II the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition this subunit in combination with several other polymerase

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Description

Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3

Isoforms of protein inhibitor of activated STAT 2 enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein

This protein also is an endoplasmic reticulum transmembrane protein that helps regulate ceramide transport from the endoplasmic reticulum to the Golgi apparatus

The encoded protein contains a Gla (gamma carboxyglutamate) domain

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Rpb1 CTD(Phospho-Thr4) Rabbit Polyclonal Antibody, 50ul[BT-AP12338] Immunology Mutations in this gene areThis gene encodes the largest subunit of RNA polymerase II the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition this subunit in combination with several other polymerase

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