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CCAR1 Polyclonal Antibody, 100ul Bacterial Expression Mutations in this gene are

SKU: 95713822958

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CCAR1 Polyclonal Antibody, 100ul Bacterial Expression Mutations in this gene areMay be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14 3 3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and or cell proliferation.,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence Contaminating sequence. Potential poly A sequence.,Contains 1 SAP

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Description

Mutations in this gene are associated with Nijmegen breakage syndrome| an autosomal recessive chromosomal instability syndrome characterized by microcephaly| growth retardation| immunodeficiency| and cancer predisposition

Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling

differ in the number of N-terminal zinc finger motifs that bind DNA and in nuclear localization signal presence

The testis-specific serine/threonine-protein kinase 4 is thought to be involved in spermatogenesis via stimulation of the CREB/CRE responsive pathway through phosphorylation of the cAMP responsive element binding protein transcription factor

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CCAR1 Polyclonal Antibody, 100ul Bacterial Expression Mutations in this gene areMay be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14 3 3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and or cell proliferation.,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence Contaminating sequence. Potential poly A sequence.,Contains 1 SAP

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