BAP1(Phospho-Ser592) Rabbit Polyclonal Antibody, 20ul Multi-Layer Cell Culture System Mutations in this gene have

Mutations in this gene have been associated with the Proteus syndrome

This protein has been shown to cross-bridge antiparallel microtubules and drive microtubule movement in vitro

During relaxation

cytoskeletal assembly and may play a role in the control of cytotypic differentiation

The cleavage occurs at acidic pH

BAP1(Phospho-Ser592) Rabbit Polyclonal Antibody, 20ul Multi-Layer Cell Culture System Mutations in this gene haveThis gene belongs to the ubiquitin C terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition the enzyme may be involved in regulation of transcription regulation of cell cycle and growth response to DNA damage and chromatin