CRADD Polyclonal Antibody, 20ul Thermal Control The encoded protein (ALMS1

The encoded protein (ALMS1

NSF functions as an ATPase and it is a part of the 20S membrane fusion apparatus with the vesicular SNAP receptor (v-SNARE) synaptobrevin

which houses over 700 genes and comprises nearly 3% of the human genome

The import of proteins into the nucleus is a process that involves at least 2 steps

The encoded preproprotein is proteolytically processed to generate the mature protease

CRADD Polyclonal Antibody, 20ul Thermal Control The encoded protein (ALMS1This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2 ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1 RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with mental retardation. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants.