p53 Polyclonal Antibody, 100ul[BT-AP06808] Peptide Library APP1 (activated-platelet protein-1)

APP1 (activated-platelet protein-1)

Two transcript variants encoding different proteins have been found for this gene

which is an integral part of the anchoring filaments that connect epithelial cells to the underlying basement membrane

possibly by regulating the size of the clathrin cage

and they probably constitute hemangiogenic stem cells

p53 Polyclonal Antibody, 100ul[BT-AP06808] Peptide Library APP1 (activated-platelet protein-1)TP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.