Granuphilin Polyclonal Antibody, 50ul Multiplex Immunoassays Autoantibodies against this protein have

Autoantibodies against this protein have been found in patients with cancer or graft versus host disease

and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane

A recent study showed this gene to be an authentic stop codon readthrough target| and that its mRNA can give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon

GPRIN2 is a Protein Coding gene

The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes

Granuphilin Polyclonal Antibody, 50ul Multiplex Immunoassays Autoantibodies against this protein haveSYTL4 (synaptotagmin like 4) encodes a member of the synaptotagmin like protein family. Members of this family are characterized by an N terminal Rab27 binding domain and C terminal tandem C2 domains. The encoded protein binds specific small Rab GTPases and is involved in intracellular membrane trafficking. This protein binds Rab27 and may be involved in inhibiting dense core vesicle exocytosis. Alternate splicing results in multiple transcript