IGF-IIR Polyclonal Antibody, 100ul[BT-AP04393] Centrifuge Tube (Bottle) The protein encoded by this

The protein encoded by this family member contains a signal peptide

The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway

In contrast

and a latent TGF-beta binding protein

At the cell surface| these modifications have roles in cell-cell and cell-substrate interactions| bacterial adhesion| and protein targeting (Samyn-Petit et al

IGF-IIR Polyclonal Antibody, 100ul[BT-AP04393] Centrifuge Tube (Bottle) The protein encoded by thisIGF2R encodes a receptor for both insulin like growth factor 2 and mannose 6 phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with