Oct-3/4 Polyclonal Antibody, 20ul[BT-AP06332] Enzyme-Linked Immunosorbent Assay (ELISA) Mutations in ITPR1 cause spinocerebellar
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Oct-3/4 Polyclonal Antibody, 20ul[BT-AP06332] Enzyme-Linked Immunosorbent Assay (ELISA) Mutations in ITPR1 cause spinocerebellarPOU5F1 (POU class 5 homeobox 1) encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of POU5F1 in adult tissues is associated with tumorigenesis. POU5F1 can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non AUG
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