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STEAP2 Polyclonal Antibody, 50ul Dry Bath DNA accessibility is regulated via

SKU: 94368264884

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PLN185.00 PLN213.00

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STEAP2 Polyclonal Antibody, 50ul Dry Bath DNA accessibility is regulated viaSTEAP2 is a member of the STEAP family and encodes a multi pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression.

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Description

DNA accessibility is regulated via a complex set of post-translational modifications of histones| also called histone code| and nucleosome remodeling

The notch 2 functions as a receptor for membrane bound ligands

the interaction is direct and specific for CENPA since it does not interact with H3

The functional enzyme is thought to be a homodimer which uses FAD as a cofactor

ATP5J2 has multiple pseudogenes

STEAP2 Polyclonal Antibody, 50ul Dry Bath DNA accessibility is regulated viaSTEAP2 is a member of the STEAP family and encodes a multi pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression.

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