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FA11 Rabbit Polyclonal Antibody, 50ul[BT-AP09939] Peptide Synthesis The encoded protein (coenzyme Q8B)

SKU: 9416747104

4.3
SEK162.00 SEK209.00

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FA11 Rabbit Polyclonal Antibody, 50ul[BT-AP09939] Peptide Synthesis The encoded protein (coenzyme Q8B)This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains resulting in activated factor XIa a serine protease

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Description

The encoded protein (coenzyme Q8B) has a complete protein kinase catalytic domain

Cyclin L1 plays a role in the mRNA splicing process regulation

The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene

The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5

Has over 50-fold higher inhibitory activity when phosphorylated

FA11 Rabbit Polyclonal Antibody, 50ul[BT-AP09939] Peptide Synthesis The encoded protein (coenzyme Q8B)This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains resulting in activated factor XIa a serine protease

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