GRK 2(Phospho Ser685) Polyclonal Antibody, 100ul Sampling Tubes These proteins associate with Amphiphysin

These proteins associate with Amphiphysin

Contains 1 IRS-type PTB domain

Cdks are considered potential targets for anti-cancer therapy due to their involvement with cell cycle regulation

The final form of this protein consists of noncovalently bound N- and C-terminal chains

Defects in ACTC1 have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC)

GRK 2(Phospho Ser685) Polyclonal Antibody, 100ul Sampling Tubes These proteins associate with AmphiphysinThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.