p21(Phospho Thr145) Polyclonal Antibody, 20ul PCR Series Mutations in this gene are
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p21(Phospho Thr145) Polyclonal Antibody, 20ul PCR Series Mutations in this gene areThis gene encodes a potent cyclin dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin cyclin dependent kinase2 or cyclin dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53 dependent cell cycle G1 phase arrest in response to a variety of
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