Rb Polyclonal Antibody, 100ul[BT-AP07693] sgRNA Library Construction Alpha-type protein kinase family

Alpha-type protein kinase family

Members of this protein family have an affinity for beta-galactosides

and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences

CD58 encodes a member of the immunoglobulin superfamily

The encoded protein is similar in sequence to another G protein-coupled receptor (GPR7)

Rb Polyclonal Antibody, 100ul[BT-AP07693] sgRNA Library Construction Alpha-type protein kinase familyThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.