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LRRK2 Polyclonal Antibody, 100ul Cell fragmentation and collection The phosphorylation state of this

SKU: 92832893190

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LRRK2 Polyclonal Antibody, 100ul Cell fragmentation and collection The phosphorylation state of thisThis gene is a member of the leucine rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine rich repeat (LRR) domain, a kinase domain, a DFG like motif, a RAS domain, a GTPase domain, a MLK like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease 8.

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Description

The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin

its full length nature is not known

This protein causes differentiation of brain cells

The protein belongs to the S21E family of ribosomal proteins

and maps to human chromosome 17q21

LRRK2 Polyclonal Antibody, 100ul Cell fragmentation and collection The phosphorylation state of thisThis gene is a member of the leucine rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine rich repeat (LRR) domain, a kinase domain, a DFG like motif, a RAS domain, a GTPase domain, a MLK like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease 8.

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