FAS Monoclonal Antibody, 100ul Cell Transfection Mutations in t

Mutations in t

YOD1 deubiquitinase by YOD1 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain

and the protein encoded by this gene is thought to be involved in pre-mRNA splicing and in signal transduction

It is predicted to have a cytoplasmic C-terminus| 13 transmembrane domains| and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus

Naturally occurring read-through transcription exists between upstream ATP5J2 (ATP synthase| H+ transporting| mitochondrial Fo complex| subunit F2) and this gene

FAS Monoclonal Antibody, 100ul Cell Transfection Mutations in tThe protein encoded by this gene is a member of the TNF receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death inducing signaling complex that includes Fas associated