Flt3 Polyclonal Antibody, 20ul[BT-AP03282] Cell Culture Flasks Unlock DNA for new discoveries

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The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily

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It was previously thought that a related gene

congenital myopathy with excess of thin myofilaments

Flt3 Polyclonal Antibody, 20ul[BT-AP03282] Cell Culture Flasks Unlock DNA for new discoveriesFLT3 encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis,