BUB1B Polyclonal Antibody, 50ul Gene Synthesis Diseases associated with PGLS include

Diseases associated with PGLS include lymphatic system disease

A promoter region between this gene and the 5'-adjacent RGS19 (regulator of G-protein signaling 19) gene on the opposite strand functions bi-directionally as a core-promoter for both genes

PLD4 (Phospholipase D Family Member 4) is a Protein Coding gene

The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21)

PTM:Phosphorylation at 'Thr-103' and 'Ser-573' is followed by proteasomal degradation

BUB1B Polyclonal Antibody, 50ul Gene Synthesis Diseases associated with PGLS includeThis gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase promoting complex cyclosome (APC C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.