Phospho-AP-1 (T239) Polyclonal Antibody, 20ul Custom RNA Oligos also known as hereditary hyperekplexia

also known as hereditary hyperekplexia or congenital stiff-person syndrome

A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome

Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region

and function as ligand-activated cation channels

Two alternative transcripts encoding the same protein have been described

Phospho-AP-1 (T239) Polyclonal Antibody, 20ul Custom RNA Oligos also known as hereditary hyperekplexiaJUN is the putative transforming gene of avian sarcoma virus 17. It encodes Jun proto oncogene, AP 1 transcription factor subunit which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. JUN is intronless and is mapped to 1p32 p31, a chromosomal region involved in both translocations and deletions in human malignancies.