RUNX1(Phospho Ser249) Polyclonal Antibody, 50ul Serum & Sample Tubes The protein encoded by this

The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit

The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking

This gene is located in the calcium-binding phosphoprotein gene cluster on chromosome 4

also known as S-antigen

islet beta cells

RUNX1(Phospho Ser249) Polyclonal Antibody, 50ul Serum & Sample Tubes The protein encoded by thisCore binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have