TPD53 Polyclonal Antibody, 100ul Centrifuges HSF2BP may therefore be involved

HSF2BP may therefore be involved in modulating HSF2 activation

Alternatively spliced transcript variants have been reported for this gene

This gene has a pseudogene on chromosome 7

It is expressed in a broad range of cells and tissues in adult animals

but not in normal immortal melanocytes

TPD53 Polyclonal Antibody, 100ul Centrifuges HSF2BP may therefore be involvedThis gene encodes a member of a family of proteins that contain coiled coil domains and may form hetero or homomers. The encoded protein is involved in cell proliferation and calcium signaling. It also interacts with the mitogen activated protein kinase kinase kinase 5 (MAP3K5 ASK1) and positively regulates MAP3K5 induced apoptosis. Multiple alternatively spliced transcript variants have been observed.