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CD141 Polyclonal Antibody, 100ul sgRNA customized design The encoded preproprotein present in

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CD141 Polyclonal Antibody, 100ul sgRNA customized design The encoded preproprotein present inThe protein encoded by this intronless gene THBD (thrombomodulin) is an endothelial specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in THBD are a cause of thromboembolic disease, also known as inherited thrombophilia.

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Description

The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked

The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division

The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells

EPH and EPH-related receptors have been implicated in mediating developmental events| particularly in the nervous system

The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4

CD141 Polyclonal Antibody, 100ul sgRNA customized design The encoded preproprotein present inThe protein encoded by this intronless gene THBD (thrombomodulin) is an endothelial specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in THBD are a cause of thromboembolic disease, also known as inherited thrombophilia.

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