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HLA-DO Alpha Polyclonal Antibody, 100ul Biomatrix The TFIIIC2 complex is composed

SKU: 91073008403

4.5
USD123.75 USD170.75

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HLA-DO Alpha Polyclonal Antibody, 100ul Biomatrix The TFIIIC2 complex is composedHLA DOA belongs to the HLA class II alpha chain paralogues. HLA DOA forms a heterodimer with HLA DOB. The heterodimer, HLA DO, is found in lysosomes in B cells and regulates HLA DM mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.

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Description

The TFIIIC2 complex is composed of six subunits

The protein encoded by NOP56 is similar in sequence to Nop56p and is also found in the nucleolus

which shift from the inactive to the active state through the action of RALGDS (MIM 601619)

Polymorphisms in this gene have been linked to various human diseases| including IgA deficiency| common variable immunodeficiency| and premature ovarian failure

Recognizes the substrate consensus sequence

HLA-DO Alpha Polyclonal Antibody, 100ul Biomatrix The TFIIIC2 complex is composedHLA DOA belongs to the HLA class II alpha chain paralogues. HLA DOA forms a heterodimer with HLA DOB. The heterodimer, HLA DO, is found in lysosomes in B cells and regulates HLA DM mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.

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