KANK2 Polyclonal Antibody, 20ul Protein Post-translational Modification The encoded protein is a

The encoded protein is a transcription factor important for the development of the renal and urogenital systems

It may be a critical substrate for p210 (bcr/abl)

This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes

Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines

It is thought that this protein may be involved in oocyte maturation and follicular development as a homodimer or by forming heterodimers with a related protein

KANK2 Polyclonal Antibody, 20ul Protein Post-translational Modification The encoded protein is aKANK2 encodes a member of the KN motif and ankyrin repeat domains (KANK) family of proteins, which play a role in cytoskeletal formation by regulating actin polymerization. The encoded protein functions in the sequestration of steroid receptor coactivators and possibly other proteins. Mutations in this gene are associated with impaired kidney podocyte function and nephrotic syndrome, and keratoderma and woolly hair.