Frizzled-7 Polyclonal Antibody, 100ul Electrophoresis & Labeling Mutations in this gene that

Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents

It requires divalent metal ions and an intact Nudix motif for enzymatic activity

Two transcript variants encoding different isoforms (B and B') have been found for this gene

Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network

where it forms aggregates that repel neuronal processes of the same cell type

Frizzled-7 Polyclonal Antibody, 100ul Electrophoresis & Labeling Mutations in this gene thatMembers of the frizzled gene family encode 7 transmembrane domain proteins that are receptors for Wnt signaling proteins. Frizzled 7 contains an N terminal signal sequence, 10 cysteine residues typical of the cysteine rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C terminal tail with a PDZ domain binding motif. FZD7 expression may downregulate APC function and enhance beta catenin mediated