HBO1 Polyclonal Antibody, 100ul Cell Biology Multiple transcript variants encoding distinct

Multiple transcript variants encoding distinct isoforms have been identified for this gene

This gene encodes a component of the chromosomal passenger complex

This gene encodes a guanosine triphosphatase enzyme

A frequent polymorphism in the translation start codon of this gene can abolish translation and may be associated with forms of deafness

An important paralog of this gene is UBTD1

HBO1 Polyclonal Antibody, 100ul Cell Biology Multiple transcript variants encoding distinctKAT7 is a gene on chromosome 17q21. 2 that encodes a component of the HBO1 complex which is responsible for the bulk of histone H4 acetylation. Histone acetyltransferase KAT7 specifically represses AR mediated transcription; it may regulate DNA replication by chromatin acetylation and act as a coactivator of TP53 dependent transcription.