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SALL1 Polyclonal Antibody, 50ul Vortex Mixer This gene shares a bidirectional

SKU: 9030698051

4.3
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SALL1 Polyclonal Antibody, 50ul Vortex Mixer This gene shares a bidirectionalThe protein encoded by this gene is a zinc finger transcriptional repressor and may be part of the NuRD histone deacetylase complex (HDAC). Defects in this gene are a cause of Townes Brocks syndrome (TBS) as well as bronchio oto renal syndrome (BOR). Two transcript variants encoding different isoforms have been found for this gene.

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Description

This gene shares a bidirectional promoter with a paralogous gene on the opposite strand

Alternative splicing of downstream exons is also observed| which results in different forms of the stimulatory G-protein alpha subunit| a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses

Reciprocal translocations between chromosomes 22 and 17

a bipartite nuclear targeting signal

tissue specificity:Low level in normal B and T-cells

SALL1 Polyclonal Antibody, 50ul Vortex Mixer This gene shares a bidirectionalThe protein encoded by this gene is a zinc finger transcriptional repressor and may be part of the NuRD histone deacetylase complex (HDAC). Defects in this gene are a cause of Townes Brocks syndrome (TBS) as well as bronchio oto renal syndrome (BOR). Two transcript variants encoding different isoforms have been found for this gene.

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