JIP-1(Phospho Thr103) Polyclonal Antibody, 20ul Modification Enzymes The gene encoding for the

The gene encoding for the CDYL protein localizes to chromosome 6p25

Mutations in PMS2 have been associated with hereditary nonpolyposis colorectal cancer (HNPCC

CBLN1 encodes a cerebellum-specific precursor protein

and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1

This gene is a member of the alpha interferon gene cluster on the short arm of chromosome 9

JIP-1(Phospho Thr103) Polyclonal Antibody, 20ul Modification Enzymes The gene encoding for theThis gene encodes a regulator of the pancreatic beta cell function. It is highly similar to JIP 1, a mouse protein known to be a regulator of c Jun amino terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL 1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA binding transactivator of the glucose